Guardians of the Galaxy characters, Groot, Rocket Raccoon, Star-Lord, Gamora, and Drax, as well as Doctor Strange, Doctor Octopus, Green Goblin, Spider-Gwen, Spider-Man Noir, Spider-Man 2099, Captain America, Thor, Hulk, Hawkeye, Iron Man, Ms. Marvel, Ant-Man, Captain Marvel, Kang the Conqueror, and many more, appear in LEGO Marvel Super Heroes 2.